I try the new Profhilo protocol for eyes at Clinic 42 (and spoiler: I love it)


Several years ago I visited the inimitable Dr. Ellen Selkon at Clinic 42 to try a then-brand new injectable beauty option known as Profhilo. From Italy and a game changer for the industry, the Profhilo treatment provided an innovative and exciting new approach to anti-ageing known as “biomodelling”. This refers to the remodelling of the extracellular matrix in terms of elasticity and support, and clinical data confirms resulting improvements in skin texture, elasticity and hydration with an immediate tightening effect.
Beyond plumping cheeks and filling in lines, cosmetic injectable treatments have now evolved to achieve skin structural changes by stimulating the natural tissue and influencing fibroblast activity. Profhilo is at the forefront of this next-gen offering and its popularity has gone global with very good reason – and I was immediately a raving fan.

So what’s in it?
The Profhilo formula contains an ultra-pure hyaluronic acid, the component of our skin responsible for retaining moisture. As we age, our natural production of hyaluronic acid decreases more and more by the year. Topical applications using quality products containing hyaluronic acid definitely help, but adding a treatment like Profhilo into the mix will up your skin game dramatically.
Uniquely, Profhilo combines both high molecular weight and low molecular weight hyaluronic acid, which delivers a dual action that nourishes the dermal cells and actually remodels the skin. The combo is a first, and never seen before in an injectable product. By directly delivering unique levels of HA using patented technology, it hydrates from the inside out while simultaneously stimulating collagen and elastin production to tighten lax skin, change skin quality and eliminate crêpey-ness. Thanks to a thermal stabilisation process, the solution flows freely, integrating within the subcutaneous tissue and the dermis making it capable of rejuvenating areas that were previously a challenge, such as the neck, arms and forehead.
Dr. Ellen first heard of the Profhilo treatments at a conference in Sweden five plus years ago, so was beyond excited to be able to work with it once it arrived in New Zealand. “I’d followed the studies and was quite confident to start using it straight away,” she told me, “and the fact that it is so easy to use was an added bonus. We’ve all been blown away by the results we’ve achieved with it, especially on the neck which is such a difficult area to treat.”

Same Profhilo, new treatment area
Often called the ‘Profhilo Glow’ or the ‘Profhilo Filter’ by fans of the treatment, stellar results have been seen in patients of all ages. Amazing when combined with Botox or dermal fillers but an incredible treatment all on its own, the phenomenal success of Profhilo and its sister injectable, Profhilo Structura sparked waitlists and lead to global shortages – as the ‘after’ shots really do speak for themselves. And now Dr. Ellen has delivered another national first with a groundbreaking treatment protocol using Profhilo that targets the delicate under-eye and lip areas.
“Filler in these zones can look puffy or visible due to how thin the skin is,” she says. “This Profhilo® approach is different — it improves texture, boosts collagen and elastin, and delivers noticeable refinement without volume overload. It is a treatment that will gradually, over time, improve the skin and tissue quality in this difficult to treat area.”

Where do I sign up?
I’ve been long frustrated my under-eye area which, after years of Botox, has thinned dramatically and lacks hydration no matter how many stellar (and spendy!) topical formulas I throw at it. Notoriously one of the most challenging areas to treat in cosmetic medicine, I jumped at the chance to try Profhilo for my eye area, and after a consult with Dr. Ellen I was one of the first in the chair at Clinic 42 and super keen to give it a whirl.

What does it feel like?
I am very familiar with the usual set of ten jabs (five in either side of the face) that is the standard Profhilo protocol, repeated four weeks later. It’s a treatment that is definitely on the ouchey side, and I’m not going to lie – around the eye I definitely felt the stinging sensation as the liquid is pushed under the skin. I had been warned of puffiness and a few little lumps that will dissipate over 24-48 hours, the latter hardly noticeable alongside a few dots visible for the rest of the day. These were easily covered or well… ignored!
One site of puffiness definitely lingering for a good week, and did the same after my second session, but with zero bruising to deal with it was a small price to pay for (spoiler alert!) some seriously impressive results.

The takeaway
A good three weeks after my last treatment, and the fine lines and areas of concern around my eyes have improved dramatically. Nothing is frozen and I still most definitely look like me, but the softening is significant and the likes of concealer that much easier to apply.
Consider me shamelessly obsessed, and yep, I’ve been recommending this to all in sundry who are concerned about the thinning of an already delicate area that until now, felt nigh on impossible to treat.
Already a huge fan of Profhilo, I’m now irrevocably hooked x

If you’re keen to give this a whirl, head to Clinic 42 to find out more.

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